Mystical Creatures of Monster High Witch Hitch: Allies or Foes?

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Monster High is a popular franchise created by Mattel, featuring a group of unique characters who are all descendants of famous monsters. One of the most iconic characters from the Monster High franchise is a character named Draculaura, who is a teenage vampire and the daughter of Dracula. Draculaura is portrayed as a girly and fashion-conscious character, who loves dressing up and wearing cute outfits. She is known for her pink and black color scheme, and her signature heart-shaped birthmark. In terms of her personality, Draculaura is depicted as friendly, sweet, and a bit clumsy. In the Monster High web series and movies, Draculaura plays a central role as one of the main characters.

Witch riding a broom publication

In the Monster High web series and movies, Draculaura plays a central role as one of the main characters. She is often depicted as one of the more compassionate and understanding characters, always willing to help her friends and stand up for what is right. Draculaura is also known for her love of dancing and her ability to light up a room with her positive energy.

The Origin Of Witches Riding Broomsticks: Drugs From Nature, Plus Shakespeare

Today's timely post is an updated version of a story I wrote back in 2007 at my Terra Sigillata blog on ScienceBlogs.com, modified here at Forbes on Halloween in 2012, the first month I wrote in this space, then updated further with what I've learned since. But this story is one that I have been teaching in my pharmacology classes since 1992 at the University of Colorado School of Pharmacy and Pharmaceutical Sciences.

Such an image is so imprinted in our culture that few may wonder where it originated. Pharmacology, . [+] my friends. Natural products pharmacology. Image Credit: Shutterstock

Have you ever wondered, especially on Halloween, why witches are depicted as riding on brooms through the nighttime sky?

The truth lies in science -- pharmacology, actually, and natural products pharmacology at that.

Unfortunately, it's a story you may find difficult explaining to the kids.

The excerpts I'm about to give you come from a superb and accessible pharmacology text from 1992 entitled, Murder, Magic, and Medicine, by John Mann, host of the BBC Radio 4 series by the same name.

Witches

"Double, double toil and trouble
Fire burn and cauldron bubble" - Macbeth IV, i

The historical depiction of witches riding broomsticks has its origins in hallucinogenic plant pharmacology, as popularized by Shakespeare, but the indigenous knowledge predates even him.

Hallucinogenic chemicals called tropane alkaloids are made by a number of plants including Atropa belladonna (deadly nightshade), Hyoscyamus niger (henbane), Mandragora officinarum (mandrake) and Datura stramonium (jimsonweed). During the Middle Ages, parts of these plants were used to make "brews," "oyntments" or "witches' salves" for witchcraft, sorcery and other nefarious activities.

Somewhere along the line, the observation was made that the hallucinogenic compounds, hyoscine in particular -- also known as scopolamine -- could be absorbed through sweat glands in the armpit or via the mucus membranes of the rectum or vaginal area. As compared to eating the plants or drinking their extracts, axial, rectal and vaginal routes of administration also bypassed the first cycle of rapid metabolism by the liver (and severe intestinal discomfort).

This stock image from Shutterstock carries the caption, "Cleanup housework concept. Funny cleaning . [+] lady young woman mopping floor, holding mop jumping flying on white background." Each generation has appropriated the image of a woman astride a broomstick or, in this case, a mop.

(For my front-row students who always kept me on my toes, some pharmacology texts state that rectal drug administration does expose as much as half of the absorbed drug to first pass metabolism as the superior hemorrhagic vein drains into the mesenteric circulation. So, the vulvovaginal and axial means of application detailed below are the ones that truly overcome first-pass hepatic metabolism.)

Broomsticks

Just how did the alleged witches apply said ointments? According to Mann, the earliest clue comes from a 1324 investigation of the case of Lady Alice Kyteler:

"In rifleing the closet of the ladie, they found a pipe of oyntment, wherewith she greased a staffe, upon which she ambled and galloped through thick and thin."

And from the fifteenth-century records of Jordanes de Bergamo:

"But the vulgar believe, and the witches confess, that on certain days or nights they anoint a staff and ride on it to the appointed place or anoint themselves under the arms and in other hairy places."

These passages account for why so many of the pictures of the time depict partially clothed or naked witches "astride their broomsticks," as shown in the woodcut image featured here.

Shown in Mann's book with the caption, "A seventeenth-century engraving of a witch being prepared . [+] for the Sabbat. Note the administration of the salve." Credit: Wellcome Institute Library, London

Why Flying?

But what about the issue of flying on said broomsticks?

The tropane alkaloid hallucinogens tended to cause sleep, but with dreams that involved flying, "wild rides" and "frenzied dancing." A 1966 description of tropane alkaloid intoxication was offered by the Gustav Schenk:

"My teeth were clenched, and a dizzied rage took possession of me. but I also know that I was permeated by a peculiar sense of well-being connected with the crazy sensation that my feet were growing lighter, expanding and breaking loose from my own body. Each part of my body seemed to be going off on its own, and I was seized with the fear that I was falling apart. At the same time I experienced an intoxicating sensation of flying. I soared where my hallucinations - the clouds, the lowering sky, herds of beasts, falling leaves. billowing streamers of steam and rivers of molten metal - were swirling along."

So, these psychosensory experiences of flying were associated with boiled up hallucinogenic plants applied to the vulvovaginal area with a broomstick, probably used to mix the concoction.

An aside: Legendary pharmacologist, Susan Band Horwitz, PhD, reminded me a few years ago that the same passage from Macbeth quoted above also contains a reference to the source of one of our most useful natural product anticancer drugs, paclitaxel (Taxol).

. . .Liver of blaspheming Jew,

Gall of goat and slips of yew. . .

In 1979, Dr. Horwitz and her then-doctoral student, Peter Schiff, and Jane Fant, published in Nature the seminal report demonstrating that taxol acts by promoting microtubule polymerization to the point that tumor cells cannot coordinate chromosomal segregation.

It works this way in everyone, not just witches.

I was honored to work from 2002 to 2008 with the two gents who isolated Taxol from the Pacific yew and showed its anticancer activity, the late Monroe Wall, PhD, and Mansukh Wani, PhD.

I never cease to be amazed or impressed by how much of our folk history is influenced by drugs from nature -- natural products -- used in cultural or medical rituals. The fact that plants and other organisms make chemicals that affect human biology triggered my own interests in this field. Over nearly 30 years of working in pharmacology and toxicology, I spent the bulk of my time working with chemists far more talented than I trying to discern if the natural world held more anticancer drugs for us.

Did this post pique your interest? You can learn more about the colorful convergence of drugs and history -- you owe yourself the indulgence of John Mann's book.

With some melancholy, I also note that Halloween 2017 marks the shuttering of ScienceBlogs, the first major blogging network featuring scientists, launched in January 2006 by Seed Media Group. The invitation from Katherine Sharpe (and her then-boss, Christopher Mims (now at WSJ)) to bring my five-month-old blog to their second cohort in June 2007 unwittingly began my road out of the lab and science administration to write for you, Dear Reader, who I couldn't otherwise reach from the lecture hall.

The intervening decade has seen a logarithmic expansion of scientist-writers online geared to the general public. For many of us, this was a logical extension of our professional mission and personal need to share our enthusiasm with anyone who'd listen and/or read. (Of course, you can also read propaganda veiled as science. Discerning objective scientific information from that with an economic agenda has become more challenging, not less.)

But I consider myself fortunate ('blessed' as we say in the American South), to have been an early part of this science communication revolution, and with gratitude to Forbes Senior Editor Matthew Herper who, in October 2012, invited me to bring these stories to this global lecture hall.

Such an image is so imprinted in our culture that few may wonder where it originated. Pharmacology, . [+] my friends. Natural products pharmacology. Image Credit: Shutterstock
Monster high wotch hitch

One of the significant aspects of Draculaura's character is her relationship with her boyfriend Clawd Wolf, who is the older brother of another Monster High character, Clawdeen Wolf. Their love story is often a focal point in the storyline of the Monster High franchise, showcasing the challenges and joys of teenage romance. Overall, Draculaura has become a beloved character among Monster High fans worldwide. Her unique personality, fashion style, and of course, her vampire heritage, have made her a standout character in the franchise. Whether it's watching her adventures in the web series or collecting her dolls and merchandise, Draculaura has captured the hearts of fans of all ages..

Reviews for "Witchy Accessories: Must-Have Items for Every Monster High Witch Hitch Fan"

- Sarah - 1 star - I was really disappointed with Monster High Witch Witch. The story was completely all over the place and the characters were flat and uninteresting. The plot was so confusing that I had a hard time keeping track of what was happening. I couldn't connect with any of the characters and the dialogue felt forced and unnatural. Overall, I found the whole experience to be a waste of time and would not recommend it to anyone.
- Tom - 2 stars - I thought Monster High Witch Witch would be a fun and entertaining read, but unfortunately, it fell short of my expectations. The pacing of the story was extremely slow, and it took forever for anything interesting to happen. The writing style was also lackluster and didn't engage me as a reader. Additionally, I found the character development to be quite weak, and I couldn't bring myself to care about any of them. Overall, I was left feeling bored and unsatisfied with this book.
- Megan - 2 stars - I had high hopes for Monster High Witch Witch, but it just didn't deliver. The concept was intriguing, but the execution was lacking. The writing was dull, and the plot felt disjointed. The pacing was off, with long stretches of nothing happening followed by sudden, rushed action. The characters were also poorly developed, and I struggled to connect with them. I'm disappointed that I didn't enjoy this book more, as I was expecting a fun and engaging read.
- Brian - 1 star - I really disliked Monster High Witch Witch. The story felt like a jumbled mess, and I struggled to follow what was happening. The characters were one-dimensional and lacked depth. The dialogue was forced and unnatural, and I couldn't relate to anything that was being said. Overall, I found this book to be a tedious and unenjoyable read. I would not recommend it to anyone who is looking for a well-written and engaging story.

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